Resolved - Some users reported seeing the following message when attempting to place a call (after validating Edges and trunks operational):
"No primary or secondary Edges are assigned. Only in-service Edges associated with the Site will be assigned. Verify the 'Sites with Edges' configuration for the Phone's site."

While the issue appears to have affected only a small number of orgs, fix actions have been implemented to reduce further impact. If users should receive this message, the mitigation step is to change the site associated to the phones from "use this site" to "uses these sites" selecting the site. If additional assistance is needed, please contact product support.
Sep 18, 09:33 EDT